A blockchain-based audit approach for encrypted data in federated learning

The development of data-driven artificial intelligence technology has given birth to a variety of big data applications. Data has become an essential factor to improve these applications. Federated learning, a privacy-preserving machine learning method, is proposed to leverage data from different data owners. It is typically used in conjunction with cryptographic methods, in which data owners train the global model by sharing encrypted model updates. However, data encryption makes it difficult to identify the quality of these model updates. Malicious data owners may launch attacks such as data poisoning and free-riding. To defend against such attacks, it is necessary to find an approach to audit encrypted model updates. In this paper, we propose a blockchain-based audit approach for encrypted gradients. It uses a behavior chain to record the encrypted gradients from data owners, and an audit chain to evaluate the gradients’ quality. Specifically, we propose a privacy-preserving homomorphic noise mechanism in which the noise of each gradient sums to zero after aggregation, ensuring the availability of aggregated gradient. In addition, we design a joint audit algorithm that can locate malicious data owners without decrypting individual gradients. Through security analysis and experimental evaluation, we demonstrate that our approach can defend against malicious gradient attacks in federated learning.     

四氢姜黄素经PI3K/Akt信号通路对人血小板活化和聚集的调控作用

目的：探讨姜黄素的主要肠道代谢物四氢姜黄素（tetrahydrocurcumin，THC）对血小板活化和聚集的影响及其可能的分子机制。方法：在体外实验中，用不同浓度的THC（0、0.5、1、10 μmol/L）提前与健康人纯化血小板共同孵育40 min，然后加入凝血酶激活血小板2 min，用流式细胞术测定血小板表面CD62P和CD63的表达量，用酶联免疫吸附法测定血小板释放血小板因子-4（platelet factor-4，PF4）和趋化因子配体-5（chemokine ligand 5，CCL5）水平，用血小板聚集仪检测血小板释放ATP水平和血小板最大聚集率，用Western blot蛋白免疫印迹法检测血小板磷酸肌醇-3-激酶（phosphoinositide 3-kinase，PI3K）和Akt蛋白的磷酸化水平。结果：与模型组（血小板悬液中加入0.05%二甲基亚砜）相比，THC能抑制凝血酶诱导的血小板表面CD62P和CD63的表达，抑制PF4、CCL5和ATP的释放，降低血小板最大聚集率，下调PI3K和Akt蛋白的磷酸化水平，且呈浓度依赖效应，其中10 μmol/L的浓度下作用效果显著（P＜0.01、P＜0.001）。PI3K的特异性激动剂740 Y-P可部分逆转THC对PF4和CCL5释放和血小板聚集的抑制作用（P＜0.05、P＜0.01）。结论：THC具有显著抑制血小板活化和聚集的作用，其机制可能是THC可下调PI3K/Akt介导的信号通路。     

Shaking table study on seismic behavior of MSE wall with inclined backfill soils reinforced by polymeric geostrips

In this study, the seismic behavior of a mechanically stabilized earth (MSE) wall with inclined backfill is investigated under sinusoidal acceleration excitations using a series of 1-g shaking table tests performed on the MSE model of 150 cm in height reinforced with polymeric geostrips. The effects of the stiffness of the reinforcement and slope angles of the backfill soil on the acceleration amplification factor (RMSA), the lateral displacement of the wall, the surface displacement of the backfill, the distribution of dynamic earth pressure along the height of reinforced wall and the strain distributions on the surfaces of the polymeric geostrips in three planes of the wall are investigated. The experimental results show that the dynamic earth pressure determined by traditional pseudo-static approaches leads to overestimated values. In addition, increasing the inclination angle of backfill soil results in the increase of surface settlement, lateral wall displacements, soil dynamic earth pressures, acceleration amplification factors and strains on the polymeric geostrip materials. The stiffness of the polymeric geostrip material has a negligible effect on the displacement, dynamic earth pressures and failure surface geometry.     

AQP3 Increases Intercellular Cohesion in NSCLC A549 Cell Spheroids through Exploratory Cell Protrusions

Tumor cell aggregation is critical for cell survival following the loss of extracellular matrix attachment and dissemination. However, the underlying mechanotransduction of clustering solitary tumor cells is poorly understood, especially in non-small cell lung cancers (NSCLC). Here, we examined whether cell surface protrusions played an important role in facilitating the physical contact between floating cells detached from a substrate. We employed poly-2-hydroxyethyl methacrylate-based 3D culture methods to mimic in vivo tumor cell cluster formation. The suprastructural analysis of human NSCLC A549 cell spheroids showed that finger-like protrusions clung together via the actin cytoskeleton. Time-lapse holotomography demonstrated that the finger-like protrusions of free-floating cells in 3D culture displayed exploratory coalescence. Global gene expression analysis demonstrated that the genes in the organic hydroxyl transport were particularly enriched in the A549 cell spheroids. Particularly, the knockdown of the water channel aquaporin 3 gene (AQP3) impaired multicellular aggregate formation in 3D culture through the rearrangement of the actomyosin cytoskeleton. Moreover, the cells with reduced levels of AQP3 decreased their transmigration. Overall, these data indicate that cell detachment-upregulated AQP3 contributes to cell surface protrusions through actomyosin cytoskeleton remodeling, causing the aggressive aggregation of free-floating cells dependent on the property of the substratum and collective metastasis.     

Luminescent Solar Concentrators Based on Aggregation Induced Emission

A promising path to cost-effective photovoltaic (PV) systems is sunlight concentration. Over classical non-imaging geometrical concentrators, luminescent solar concentrators (LSCs) possess several advantages: low cost and weight, elevated theoretical concentration factors and aptitude to efficiently working with diffuse light without tracking or cooling equipment. Although considerable progress has been made, current LSC-PV systems attain low power conversion efficiencies due to critical processes that hinder their ability to deliver light to PV cells including fluorescence quenching due to dye aggregation. To overcome this issue, fluorophores with aggregation induced emission (AIEgens) have been proposed thanks to their high Stokes shift and quantum yield in the solid state. In this review, the current state of knowledge concerning the preparation of LSCs based on AIEgens is summarized with special reference on the strategy adopted aimed at increasing the absorption bandwidth while maximizing the solar collection.     

带权决策表的属性约简

属性约简是粗糙集理论的重要应用。考虑将决策表中的每行都作为一条决策规则时，若把表中出现相同决策规则的次数作为权，可得到带权决策表。提出了关于带权决策表的正域约简相应的辨识矩阵并给出了证明，从而得到了约简算法。相比于决策表中的正域约简时发现，通过将决策表转化为带权决策表后，再利用算法1进行约简时，其在一定程度上优于前者。提出了近似分类精度约简相应的辨识矩阵并给出了证明。对于2个算法，在选取的UCI数据集上进行了实验验证。通过实验进一步说明了所提出算法的可行性和有效性。     

机翼极限环颤振的CFD/CSD全隐式紧耦合方法

针对轴承振动实时状态监控的需要，从符号动力学角度提出了符号聚合近似与Lempel-ziv复杂度（SAX-LZC）融合的振动监控参数。首先，以Logistic映射和Duffing方程为对象，从理论角度验证了SAX-LZC对动力学结构表征的准确性，并验证了该指标的抗噪能力和计算效率；其次，将SAX-LZC指标与信息熵、样本熵、多分段Lempel-ziv复杂度等动力学参数性能进行了综合对比；最后，从实验角度对轴承早期微弱异常进行了监测，并对轴承典型故障进行了特征提取。理论研究结果表明，SAX-LZC具有动力学结构表征准确、抗噪能力好、计算高效简洁等优点，克服了常规动力学参数工程应用能力弱的问题。实验研究结果表明，SAX-LZC对早期微弱异常有准确的监测，对不同种类故障具有较好的区分度，弥补了时域和频域对轴承微弱故障表征能力不足的缺陷，是一种轴承振动实时状态监控与故障特征提取的有效参数。     

Emergency decision support modeling for COVID-19 based on spherical fuzzy information

Significant emergency measures should be taken until an emergency event occurs. It is understood that the emergency is characterized by limited time and information, harmfulness and uncertainty, and decision-makers are always critically bound by uncertainty and risk. This paper introduces many novel approaches to addressing the emergency situation of COVID-19 under spherical fuzzy environment. Fundamentally, the paper includes six main sections to achieve appropriate and accurate measures to address the situation of emergency decision-making. As the spherical fuzzy set (FS) is a generalized framework of fuzzy structure to handle more uncertainty and ambiguity in decision-making problems (DMPs). First, we discuss basic algebraic operational laws (AOLs) under spherical FS. In addition, elaborate on the deficiency of existing AOLs and present three cases to address the validity of the proposed novel AOLs under spherical fuzzy settings. Second, we present a list of Einstein aggregation operators (AgOp) based on the Einstein norm to aggregate uncertain information in DMPs. Thirdly, we are introducing two techniques to demonstrate the unknown weight of the criteria. Fourthly, we develop extended TOPSIS and Gray relational analysis approaches based on AgOp with unknown weight information of the criteria. In fifth, we design three algorithms to address the uncertainty and ambiguity information in emergency DMPs. Finally, the numerical case study of the novel carnivorous (COVID-19) situation is provided as an application for emergency decision-making based on the proposed three algorithms. Results explore the effectiveness of our proposed methodologies and provide accurate emergency measures to address the global uncertainty of COVID-19.     

实用型气动旋转装夹工作台的设计

该设计实例为一种气动旋转装夹工作台,详细介绍该装置的设计思路,分析其结构和动作原理。该装置在实际应用中,完全满足了特殊工况需求,性能稳定,具有一定的推广价值。     

基于Android平台利用表格布局制作简易计算器界面

Android程序设计中,有6大布局方法。文章重点论述了基于Android平台利用表格布局来制作一个简易的计算器界面,涉及详细的操作步骤,对计算器界面进行有效美化和优化,并做出总结。